LIMR Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain Type Project The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, ... Application deadline | Ongoing | Non-funded
LICAMM Differentiated response of endothelial Piezo1 channels to shear stress and hydrostatic pressure and its underlying molecular basis Type Project Mechanical forces play important roles in physiology and pathophysiology of vascular endothelial cells such as proliferation, apoptosis, mig... Application deadline | Ongoing | Non-funded
In-situ Characterisation of the Crystal Growth of Organic Materials through Microscopic Imaging, Image Processing and Machine Learning Type Project The crystal growth of organic materials is of significant importance within the speciality and fine chemical industries. This reflects its u... Application deadline | Ongoing | Non-funded
Modernity & Gender Spaces: Analyzing spatial systems and designs of public buildings and spaces with reference to gender equality Type Project The gender question remains a fundamental indicator on the transformation of modern societies as it was in the historical periods. Issues of... Application deadline | Ongoing | Non-funded
LICAMM Regulation of skin function and wound healing by pre-receptor glucocorticoid metabolism in diet-induced animal models of diabetes Type Project Diabetes is a common disease resulting in a long-term increase in blood sugar levels. Current estimates suggest 1 in 10 people globally will... Application deadline | Ongoing | Non-funded
LICAMM Hypoxia, inflammation and local steroid metabolism during wound healing: towards a new therapy for diabetic foot ulcers Type Project Type 2 diabetes is an unmet clinical need of global importance with a growing financial burden. Diabetic foot ulcers, characterized by chron... Application deadline | Ongoing | Non-funded
LIMR Genetics: Investigating the functional effect of novel genes and genetic variants in malignant hyperthermia using model systems Type Project Malignant hyperthermia (MH) is an inherited condition, where patients exposed to anaesthetic drugs are susceptible to a dramatic hyperthermi... Application deadline | Ongoing | Non-funded
The effect of inorganic nitrate on systemic energy homeostasis in a setting of perturbed energy balance: implications for diabetes and obesity. Type Project The World Health Organization estimates 500 million people worldwide are obese and over 340 million suffer from type 2 diabetes (T2D). The q... Application deadline | Ongoing | Non-funded
LIMR Genetics: Investigating the molecular basis of optic nerve degeneration in glaucoma to develop a personalized medicine strategy for treatment Type Project The optic nerve is a special sensory nerve that transmits visual impulses from the retina to the brain. Primary Open Angle Glaucoma (POAG) i... Application deadline | Ongoing | Non-funded
Computational phenotyping of cardiovascular disease following acute myocardial infarction in primary care: a large scale electronic healthcare record Type Project Cardiovascular disease remains the leading cause of death worldwide, contributing to 30% of all deaths globally. Presently, most patients wi... Application deadline | Ongoing | Non-funded
Myocardial perfusion, interstitial fibrosis and cardiomyocyte volume in the development of cardiac hypertrophy measured with contrast-enhanced MRI Type Project Recent pre-clinical studies have indicated that in addition to measures of myocardial perfusion and interstitial fibrosis, contrast-enhanced... Application deadline | Ongoing | Non-funded
Role of Neutrophils in Fibrin Structure and Function: How do Cells, Fibrin and Neutrophil Extracellular Traps (NETs) Integrate in Thrombi and Blood Cl Type Project Blood clots that cause heart attacks and strokes are composed of fibrin, platelets and red blood cells. However, white blood cells are also ... Application deadline | Ongoing | Non-funded
LICAMM Medication adherence, compliance, satisfaction and health related quality of life after myocardial infarction: EMMACE 3 and 4 trials Type Project Previous research has shown that patients with Myocardial Infarction (MI) experience decreased health related quality of life (HRQoL) compar... Application deadline | Ongoing | Non-funded
Using next-generation sequencing and CRISPR-Cas9 gene editing to investigate penetrance and phenotypic variation in inherited eye disease Type Project Human inherited retinal diseases (IRDs) result from mutations in over 250 different genes, many of them implicated by the Leeds Vision Resea... Application deadline | Ongoing | Non-funded
