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Microbiology and cell biology

PGR-RA-68

Expertise of research area
cell biology; cell signalling; dental teaching; endothelial cells; microbes; microbiology; oral biofilms; oral health; celluar biology


<h2 class="heading hide-accessible">Summary</h2>

The microbiology and cell biology research group endeavours to understand the roles of microbes and host responses in health and infectious or malignant disease.

<h2 class="heading hide-accessible">Full description</h2>

<p>Research within this research area&nbsp;includes:&nbsp;&nbsp;</p> <ul> <li> <p>Characterising and controlling oral biofilms (including metagenomic and transcriptomic analysis) to understand function as well as composition, mathematical modelling to predict biofilm behaviour, antimicrobial treatment of biofilms (including photodynamic treatment), manipulation of biofilm behaviour, development of antimicrobial materials.</p> </li> <li> <p>Understanding the role of the oral mibciome in health (and disease), particularly the roles of resident bacteria in regulating host cell responses, prebiotics and probiotics, and the environmental regulation of microbial pathogenicity.</p> </li> <li> <p>Cellular signalling (in particular the insulin-like growth factor, IGF, axis) and host defences in infectious and malignant disease; these include antimicrobial host defence peptides (eg defensins, LL-37), NK cells and neutrophils.</p> </li> <li> <p>Understanding the links between periodontal diseases and systemic disease, particularly arthritis and diabetes.</p> </li> </ul> <h2>Collaborations and partnerships</h2> <p>Members of the microbiology and cell biology research group collaborate with&nbsp;<a href="http://lmbru.leeds.ac.uk/">The Leeds NIHR Musculoskeletal Biomedical Research Unit</a>&nbsp;and&nbsp;<a href="https://biofilms.ac.uk/">National Biofilms Innovation Centre</a>.</p>

<h2 class="heading">How to apply</h2>

<p>To submit an application in this research area please complete an <a href="https://studentservices.leeds.ac.uk/pls/banprod/bwskalog_uol.P_DispLoginNon">online application form</a> and submit this alongside a research proposal, a full academic CV, degree transcripts (or marks so far if still studying) and degree certificates. If English is not your first language, you must provide evidence that you meet the Faculty&rsquo;s minimum <a href="https://medicinehealth.leeds.ac.uk/faculty-graduate-school/doc/entry-requirements-1">English language requirements</a>.</p> <p><em>We welcome applications from all suitably-qualified candidates, but UK black and minority ethnic (BME) researchers are currently under-represented in our Postgraduate Research community, and we would therefore particularly encourage applications from UK BME candidates. All scholarships will be awarded on the basis of merit.</em></p>

<h2 class="heading">Contact details</h2>

<p>For further information please contact the Graduate School Office<br /> e:&nbsp;<a href="mailto:fmhpgradmissions@leeds.ac.uk">fmhpgradmissions@leeds.ac.uk</a>, t: +44 (0)113 343 8221.</p>