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Cell and Organismal Biology


Expertise of research area
Cell and Organismal Biology; cell biology; Cryo-Electron Microscopy; Gene Regulation; Microscopy; Proteostasis

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<h2 class="heading hide-accessible">Summary</h2>

Our cell biology research aims at determining the cellular and molecular mechanisms underlying both normal cell functions and how they become dysfunctional in diseased cells and organisms.

<h2 class="heading hide-accessible">Full description</h2>

<p>In particular our research pursues a detailed understanding of the structure and function of cellular components such as membranes, organelles and the cytoskeleton as well as cellular processes including protein folding and degradation pathways, stress response mechanisms, gene regulation and protein targeting and secretion in health and disease. These themes are addressed in model systems as diverse as mammalian cells in culture, plants, worms and fruit flies. Our research themes include:&nbsp;</p> <h3><a href="">Proteostasis</a></h3> <p>Protein quality control mechanisms at the subcellular, cellular and organismal level during health, ageing and disease.</p> <h3><a href="">Membranes, Organelles and Cytoskeleton</a></h3> <p>Structure, function and dynamics of eukaryotic cytoskeleton and protein transport across organelle and cell membrane.</p> <h3><a href="">Gene Regulation</a></h3> <p>Control of gene activity, transcription and epigenetic regulation in health and disease states.</p> <p>&nbsp;</p>

<h2 class="heading">How to apply</h2>

<p>If you are interested in a&nbsp;product in this research area please search for our <a href="">research opportunities</a>.&nbsp;</p>

<h2 class="heading">Contact details</h2>

<p>For further information please contact the Graduate School Office<br /> e: <a href="mailto:">fbsgrads</a><a href=""></a>, t: +44 (0)113 343 8186</p>

<h2 class="heading heading--sm">Linked project opportunities</h2>
<h2 class="heading heading--sm">Linked funding opportunities</h2>