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Targets and therapies


Expertise of research area
cellular disease modelling; chemoprevention; nutrition; transcriptomics

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<h2 class="heading hide-accessible">Summary</h2>

We identify diseases of unmet need and focus our research on the identification and validation of target molecules, which then inform the development of small molecule screens and new biologics for use in the clinic.

<h2 class="heading hide-accessible">Full description</h2>

<p>The programme to develop a new drug starts with a health condition with no suitable medicine, a disease of unmet need. Research aimed at drug discovery starts with the identifying the target, the nucleic acid, protein or signalling pathway that might be activated or inhibited to cause a therapeutic effect. Validation of this target increases confidence that this particular molecule is causative or involved in the disease mechanism. New therapies can then be found through screening for a small molecule or biologic that is effective against that target. Our research focuses on identification and validation of target molecules which then inform the development of small molecule screens and new biologics for use in the clinic.</p>

<h2 class="heading">How to apply</h2>

<p>To submit an application in this research area please complete an <a href="">online application form</a> and submit this alongside a research proposal, a full academic CV, degree transcripts (or marks so far if still studying) and degree certificates. If English is not your first language, you must provide evidence that you meet the Faculty&rsquo;s minimum <a href="">English language requirements</a>.</p> <p><em>As an international research-intensive university, we welcome students from all walks of life and from across the world. We foster an inclusive environment where all can flourish and prosper, and we are proud of our strong commitment to student education. Across all Faculties we are dedicated to diversifying our community and we welcome the unique contributions that individuals can bring, and particularly encourage applications from, but not limited to Black, Asian, people who belong to a minority ethnic community, people who identify as LGBT+ and people with disabilities. Applicants will always be selected based on merit and ability.</em></p>

<h2 class="heading">Contact details</h2>

<p>For further information please contact the Graduate School Office<br /> e:&nbsp;<a href=""></a>, t: +44 (0)113 343 8221.</p>