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Regenerative medicine

PGR-RA-143

Expertise of research area
Bone infection; Bone regeneration; Bone scaffold; Mesenchymal stem cells; Pelvic and acetabulum reconstruction; Treatment of post fracture fixation complications


<h2 class="heading hide-accessible">Summary</h2>

We are interested in understanding the biology of human mesenchymal stem cells (MSCs) in vivo in health and disease, as a pre-requisite for the development of novel stem cell strategies. We research the in vivo phenotypes and topography of MSCS and how they can be used to treat osteoarthritis.

<h2 class="heading hide-accessible">Full description</h2>

<p>We are exploring how to use minimally manipulated MSCs for immunomodulation applications including bone repair and cartilage tissue regeneration. Improved management and treatment of osteoarthritis centres around earlier diagnosis, improved non-surgical interventions, earlier and tissue sparing interventions including acellular scaffolds, and longer lasting joint replacements, with better targeting of interventions to meet stratified patient needs, greater precision and targeting in the design and delivery of devices, as well as improved reliability of these treatments.</p>

<h2 class="heading">How to apply</h2>

<div>To submit an application in this research area please complete an <a href="https://studentservices.leeds.ac.uk/pls/banprod/bwskalog_uol.P_DispLoginNon">online application form</a> and submit this alongside a research proposal, a full academic CV, degree transcripts (or marks so far if still studying) and degree certificates. If English is not your first language, you must provide evidence that you meet the Faculty&rsquo;s minimum <a href="https://medicinehealth.leeds.ac.uk/faculty-graduate-school/doc/entry-requirements-1">English language requirements</a>.</div> <div>&nbsp;</div> <div>We welcome applications from all suitably-qualified candidates, but UK black and minority ethnic (BME) researchers are currently under-represented in our Postgraduate Research community, and we would therefore particularly encourage applications from UK BME candidates. All scholarships will be awarded on the basis of merit.</div>

<h2 class="heading">Contact details</h2>

<div>For further information please contact the Graduate School Office</div> <div>e: <a href="mailto:fmhpgradmissions@leeds.ac.uk">fmhpgradmissions@leeds.ac.uk</a>, t: +44 (0)113 343 8221.</div>