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Modelling failure mechanisms in total ankle replacement


Key facts

Type of research degree
Application deadline
Friday 10 April 2020
Project start date
Thursday 1 October 2020
Country eligibility
UK and EU
Source of funding
Doctoral training partnership
Dr Claire Brockett and Professor Sophie Williams
School of Mechanical Engineering
Research groups/institutes
Institute of Medical and Biological Engineering
<h2 class="heading hide-accessible">Summary</h2>

Total joint replacement has been a successful surgical intervention for end-stage osteoarthritis for millions of patients globally for several decades. Despite this, clinical outcomes for total ankle replacement (TAR) have been comparatively poor &ndash; with up to 20% of implants failing before 10 years. As a result, TAR &ndash; an intervention which preserves joint function &ndash; has been used less commonly than ankle fusion &ndash; an intervention which limits ankle range of motion. Further understanding of how the ankle replacements are failing, and modelling of the potential mechanisms, will inform future implant design and development &ndash; which could provide a viable replacement implant for millions of patients globally.

<h2 class="heading hide-accessible">Full description</h2>

<p>This project aims to develop experimental simulation to model the mechanisms for failure of total ankle replacement through the following activities:<br /> &nbsp;-Morphological and geometrical analysis of failed total ankle replacements<br /> - Definition of the &nbsp;functional conditions for a total ankle replacement such as biomechanical function of TAR patients; implant alignment; tissue characteristics<br /> - Development of an advanced experimental model that replicates the biomechanics of typical total ankle replacement and generates clinically relevant failure mechanisms</p>

<h2 class="heading">How to apply</h2>

<p>Formal applications for research degree study should be made online through the&nbsp;<a href="">University&#39;s website</a>. Please state clearly in the research information section&nbsp;that the research degree you wish to be considered for is &lsquo;Modelling failure mechanisms in total ankle replacement&rsquo; as well as&nbsp;<a href="">Dr Claire Brockett</a> as your proposed supervisor.</p> <p>If English is not your first language, you must provide evidence that you meet the University&#39;s minimum English language requirements (below).</p> <p><em>We welcome applications from all suitably-qualified candidates, but UK black and minority ethnic (BME) researchers are currently under-represented in our Postgraduate Research community, and we would therefore particularly encourage applications from UK BME candidates. All scholarships will be awarded on the basis of merit.</em></p>

<h2 class="heading heading--sm">Entry requirements</h2>

Applicants to research degree programmes should normally have at least a first class or an upper second class British Bachelors Honours degree (or equivalent) in an appropriate discipline. The criteria for entry for some research degrees may be higher, for example, several faculties, also require a Masters degree. Applicants are advised to check with the relevant School prior to making an application. Applicants who are uncertain about the requirements for a particular research degree are advised to contact the School or Graduate School prior to making an application.

<h2 class="heading heading--sm">English language requirements</h2>

The minimum English language entry requirement for research postgraduate research study is an IELTS of 6.0 overall with at least 5.5 in each component (reading, writing, listening and speaking) or equivalent. The test must be dated within two years of the start date of the course in order to be valid. Some schools and faculties have a higher requirement.

<h2 class="heading">Funding on offer</h2>

<p>UK/EU &ndash; Engineering &amp; Physical Sciences Research Council Studentships paying academic fees of &pound;4,600 for Session 2020/21, together with a maintenance grant of &pound;15,285 for Session 2020/21 paid at standard Research Council rates for 3.5 years. UK applicants will be eligible for a full award paying tuition fees and maintenance. European Union applicants will be eligible for an award paying tuition fees only, except in exceptional circumstances, or where residency has been established for more than 3 years prior to the start of the course. Funding is awarded on a competitive basis.</p>

<h2 class="heading">Contact details</h2>

<p>For more information regarding the project, please contact Dr Claire Brockett</p> <p>e: <a href=""></a> or t: +44 (0)113 343 7472</p> <p>For further information regarding your application, please contact the Doctoral College Admissions<br /> e:&nbsp;<a href=""></a>, t: +44 (0)113 343 5057.</p>

<h3 class="heading heading--sm">Linked funding opportunities</h3>
<h3 class="heading heading--sm">Linked research areas</h3>