PhD in evaluating the biomechanics of hip replacement surgery in patients living with obesity

This funded PhD will develop methods to evaluate total hip replacement (THR) surgery in patients with high body mass index (BMI). Although THR surgery is highly effective in most individuals, there is evidence that outcomes are poorer in some patient groups, such as those living with obesity. This study will develop computational models to examine how movement and loading affect THR performance, and what might cause early mechanical complications in groups with higher BMIs. An experimental study will be used to validate the model predictions, using the hip simulators in our world-leading laboratory facilities. <br /> <br /> The study will utilise a unique dataset of image and gait data collected previously by our collaborators at the Leeds Biomedical Research Centre (LBRC). The methods and evidence collected will help surgeons make choices on the type of THR device and how it is positioned to achieve optimum outcomes for individuals with higher BMIs. The supervision team includes engineers and clinical partners from the LBRC, providing extensive experience in the analysis tools and clinical measurement methods. The PhD is part-funded by an orthopaedic company, providing industry support and ensuring a rapid translation of findings into clinical practice.<br /> <br /> An inclusive environment and supportive application process: As an international research-intensive university, we welcome students from all walks of life and from across the world. We foster an inclusive environment where all can flourish and prosper, and we are proud of our strong commitment to student education.<br /> <br /> Interested? Guidance on how to apply , and more detailed information about the PhD is provided below.<br /> <br /> Discuss this PhD Opportunity with Ruth Wilcox by contacting: R.K.Wilcox@leeds.ac.uk<br />

<p style="margin-bottom:11px"><strong>Background:</strong></p> <p style="margin-bottom:11px">Total hip replacement (THR) surgery is a highly effective treatment to reduce pain and stiffness caused by conditions like hip osteoarthritis. However, there is increasing evidence that THR surgery has poorer outcomes in some patient groups, such as those living with obesity. Patients with a higher body mass index (BMI) have different gait patterns as well as increased loading on their joints, but there is not yet evidence on how these differences affect THR performance. This PhD study will build on computational and experimental methods developed previously at Leeds and utilise a dataset collected through the Leeds Biomedical Research Centre of patients with hip osteoarthritis and a large range of BMIs. Uniquely, this dataset contains both gait measurements and magnetic resonance imaging (MRI) of the patient’s hip anatomy.</p> <p>The new methods and evidence generated through this PhD will support surgeons to identify the most appropriate type of THR device and for individuals living with obesity or related indications.</p> <p><strong>Research objectives:</strong></p> <p>The aim of this PhD is to evaluate the risks of early mechanical failure of total hip replacement patients living with obesity using a combination of engineering tools and a unique dataset of in-vivo measurements</p> <p>The key objectives are to:</p> <ol> <li>use computational methods to determine the hip joint loads and motions from cohorts of patients with different body mass index (BMI) values, using data previously collected by the Leeds Biomedical Research centre.</li> <li>Use finite element methods based on the patient’s image and kinematic data to examine the effects of high-BMI loading conditions on the THR components and surrounding bone, that could lead to early failure.</li> <li>Validate the findings experimentally using the laboratory hip simulation equipment at Leeds.</li> <li>Work with the industry partner to identify if changes in the device selection or surgery could reduce risks of early failure and develop recommendations for surgeons.</li> </ol> <p><strong>Training and Career Development</strong></p> <p>You will gain technical skills and training in 3D image analysis, computational modelling and experimental mechanical testing. The computational aspects will include musculoskeletal modelling and finite element analysis. The laboratory study will involve use of our unique multi-axis hip simulators. Full training will be provided on all laboratory methods and the associated health and safety requirements.  </p> <p>You will also learn practical aspects of project management, scientific writing for technical or non-technical dissemination, and gain presentation skills through international conferences and group meetings. </p> <p>As part of a multidisciplinary team with supervisors from academic, clinical and industrial backgrounds, you will develop skills in the analysis of medical devices that can be applied across the HealthTech sector. We will work with you to explore your career options and develop a training plan to suit your aspirations.</p> <p><strong>Skills Required</strong></p> <p>A background in mechanical or medical engineering, or a related discipline with excellent computational skills (ideally including finite element analysis) and some laboratory experience. </p> <p><strong>The Research Environment</strong></p> <p>You will join the multi-disciplinary, dynamic Institute of Medical and Biological Engineering (IMBE) embedded within the School of Mechanical Engineering at the University of Leeds. The IMBE is a world-renowned medical engineering research centre which specialises in research and translation of medical technologies that promote ’50 active years after 50’. You will also have access to facilities and expertise from our clinical partners at the NIHR Leeds Biomedical Research Centre.  </p> <p>As a PhD student within IMBE, there will be opportunities to contribute to wider activities related to medical technologies including public and patient engagement, group training and social events. Groups of researchers working on aligned projects or using similar methods meet regularly to share ideas and best practice, and we encourage collegiate working. We will support your long term career ambitions through bespoke training and encourage external secondments, laboratory visits or participation at international conferences. </p>

<p>Formal applications for research degree study should be made online through the University’s website. Please state clearly in the Planned Course of Study section that you are applying for <em><strong>EPSRC DTP Engineering & Physical Sciences</strong></em> (if you do not apply under this programme code, your application will not be considered), in the research information section that the research degree you wish to be considered for is <em><strong>PhD in evaluating the biomechanics of hip replacement surgery in patients living with obesity</strong></em> as well as <a href="https://eps.leeds.ac.uk/mechanical-engineering/staff/192/professor-ruth-wilcox">Professor Ruth Wilcox</a> as your proposed supervisor<em><strong> </strong></em>and that the funding you wish to be considered for is <em><strong>EPSRC Faculty Doctoral Landscape Award 2026/27: Mechanical Engineering</strong></em>.</p> <p>Applications will be considered after the closing date of Friday 27 February 2026.  Potential applicants are strongly encouraged to contact supervisors for an informal discussion before making a formal application. We also advise that you apply at the earliest opportunity as the application and selection process may close early, should we receive a sufficient number of applications or that a suitable candidate is appointed.</p> <p>Please note that you must provide the following documents in support of your application by the closing date of Friday 27 February 2026:</p> <ul> <li>Full Transcripts of all degree study or if in final year of study, full transcripts to date including grading scheme</li> <li>Personal Statement outlining your interest in the project</li> <li>CV</li> </ul> <p>If English is not your first language, you must provide evidence that you meet the University's minimum English language requirements (below).</p> <p><em>As an international research-intensive university, we welcome students from all walks of life and from across the world. We foster an inclusive environment where all can flourish and prosper, and we are proud of our strong commitment to student education. Across all Faculties we are dedicated to diversifying our community and we welcome the unique contributions that individuals can bring, and particularly encourage applications from, but not limited to Black, Asian, people who belong to a minority ethnic community, people who identify as LGBT+ and people with disabilities. Applicants will always be selected based on merit and ability.</em></p>

Applicants to research degree programmes should normally have at least a first class or an upper second class British Bachelors Honours degree (or equivalent) in an appropriate discipline. The criteria for entry for some research degrees may be higher, for example, several faculties, also require a Masters degree. Applicants are advised to check with the relevant School prior to making an application. Applicants who are uncertain about the requirements for a particular research degree are advised to contact the School or Graduate School prior to making an application.

The minimum English language entry requirement for research postgraduate research study is an IELTS of 6.0 overall with at least 5.5 in each component (reading, writing, listening and speaking) or equivalent. The test must be dated within two years of the start date of the course in order to be valid. Some schools and faculties have a higher requirement.

<p>A highly competitive EPSRC Faculty Doctoral Landscape Award, in collaboration with Johnson & Johnson MedTech, providing full academic fees, together with a tax-free maintenance grant at the standard UKRI rate (£20,780 in academic session 2025/26) for 3.5 years.  Training and support will also be provided.</p> <p>This opportunity is open to UK applicants only.  All candidates will be placed into the EPSRC Faculty Doctoral Landscape Award Competition and selection is based on academic merit.</p> <p>Please note that there is 1 funded place available.  If you are successful in securing an academic offer for PhD study, this does not mean that you have been successful in securing an offer of funding.</p> <p>Please refer to the <a href="https://eur03.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.ukcisa.org.uk%2F&data=05%7C02%7CJ.S.Hewer%40leeds.ac.uk%7C07632c93c06a442dca3d08ddfc172939%7Cbdeaeda8c81d45ce863e5232a535b7cb%7C0%7C0%7C638943898649349324%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&sdata=nylGSov8jOc7hr6X%2FmfnfQPecbVUnGqgoSqVgPGy5K0%3D&reserved=0">UKCISA</a> website for information regarding Fee Status for Non-UK Nationals</p>

<p>For further information about your application, please contact PGR Admissions by email to <a href="mailto:phd@engineering.leeds.ac.uk">phd@engineering.leeds.ac.uk</a></p> <p>For further information about this project, please contact Professor Ruth Wilcox by email to <a href="mailto:R.K.Wilcox@leeds.ac.uk">R.K.Wilcox@leeds.ac.uk</a></p>