Structure formation and functions in hybrid lipid-biopolymer membranes

PGR-P-1399

Key facts

Type of research degree: PhD
Application deadline: Ongoing deadline
Project start date: Sunday 1 January 2023
Country eligibility: International (open to all nationalities, including the UK)
Funding: Non-funded
Source of funding: Other
Supervisors: Dr Amin Sadeghpour Dilmaghani
Schools: School of Food Science and Nutrition

<h2 class="heading hide-accessible">Summary</h2>

The aim of this project is to investigate the structure-related functions of biomimetic lipid-polymer hybrid nanofibre membranes. The nanofibers morphology will be controlled during electrospin processing and by incorporation of lyotropic liquid crystalline (LLC) phases. Namely, bicontinuous cubic phase comprised of intertwined channels network, hexagonal phase with tubular-shaped structures or planar lipid self-assemblies will be incorporated within the polymer fibres. Nanomechanical properties will be investigated by in-situ X-ray scattering, tensile and complementary imaging techniques. The project will then explore interactions of adipocytes and skeletal muscle cells with the nanofibre membranes and their control of cellular growth and patterning. The work will therefore contribute to innovative engineering of functional materials for a wide range of applications, including biomedical scaffolds, implants, coatings and cultured meat products.

<h2 class="heading">How to apply</h2>

<p>Formal applications for research degree study should be made online through the <a href="https://www.leeds.ac.uk/research-applying/doc/applying-research-degrees">University's website</a>. Please state clearly in the research information section that the research degree you wish to be considered for is <strong>Structure formation and functions in hybrid lipid-biopolymer membranes</strong> as well as <strong><a href="https://environment.leeds.ac.uk/faculty/staff/9450/dr-amin-sadeghpour">Dr Amin Sadeghpour</a></strong> as your proposed supervisor.</p> <p>If English is not your first language, you must provide evidence that you meet the University's minimum English language requirements (below).</p> <p><em>As an international research-intensive university, we welcome students from all walks of life and from across the world. We foster an inclusive environment where all can flourish and prosper, and we are proud of our strong commitment to student education. Across all Faculties we are dedicated to diversifying our community and we welcome the unique contributions that individuals can bring, and particularly encourage applications from, but not limited to Black, Asian, people who belong to a minority ethnic community, people who identify as LGBT+ and people with disabilities. Applicants will always be selected based on merit and ability.</em></p>

<h2 class="heading heading--sm">Entry requirements</h2>

Applicants to research degree programmes should normally have at least a first class or an upper second class British Bachelors Honours degree (or equivalent) in an appropriate discipline. The criteria for entry for some research degrees may be higher, for example, several faculties, also require a Masters degree. Applicants are advised to check with the relevant School prior to making an application. Applicants who are uncertain about the requirements for a particular research degree are advised to contact the School or Graduate School prior to making an application.

<h2 class="heading heading--sm">English language requirements</h2>

The minimum English language entry requirement for research postgraduate research study in the School of Food Science and Nutrition is an IELTS of 6.5 overall with at least 6.0 in each component (reading, writing, listening and speaking) or equivalent. The test must be dated within two years of the start date of the course in order to be valid.

<h2 class="heading">Funding on offer</h2>

<p><strong>Self-funding students are welcome to apply.</strong></p> <p><strong>UK students</strong> – The <a href="https://phd.leeds.ac.uk/funding/138-leeds-doctoral-scholarships-2021-january-deadline">Leeds Doctoral Scholarship (January deadline)</a> is available to UK applicants.  <a href="https://phd.leeds.ac.uk/funding/60-alumni-bursary">Alumni Bursary</a> is available to graduates of the University of Leeds.</p> <p><strong>Non-UK students</strong> –The <a href="https://phd.leeds.ac.uk/funding/48-china-scholarship-council-university-of-leeds-scholarships-2021">China Scholarship Council - University of Leeds Scholarship</a> is available to nationals of China. The <a href="https://phd.leeds.ac.uk/funding/73-leeds-marshall-scholarship">Leeds Marshall Scholarship</a> is available to support US citizens.  <a href="https://phd.leeds.ac.uk/funding/60-alumni-bursary">Alumni Bursary</a> is available to graduates of the University of Leeds.</p>

<h2 class="heading">Contact details</h2>

<p>For information about the project please contact <a href="mailto:a.sadeghpour@leeds.ac.uk">Dr Amin Sadeghpour</a>.</p> <p>For further information about how to apply please contact the Faculty of Environment PGR Admissions team: ENV-PGR@leeds.ac.uk</p>